Product Identifiers
Catalog # | NX17916 |
CAS Number | 1219810-16-8 |
PubChem CID | 1750826 |
Chemical Name | RSL3 |
IUPAC Name | methyl (1S,3R)-2-(2-chloroacetyl)-1-(4-methoxycarbonylphenyl)-1,3,4,9-tetrahydropyrido[3,4-b]indole-3-carboxylate |
Synonym | (1S,3R)-RSL3 |
InChI | InChI=1S/C23H21ClN2O5/c1-30-22(28)14-9-7-13(8-10-14)21-20-16(15-5-3-4-6-17(15)25-20)11-18(23(29)31-2)26(21)19(27)12-24/h3-10,18,21,25H,11-12H2,1-2H3/t18-,21+/m1/s1 |
InChIKey | TXJZRSRTYPUYRW-NQIIRXRSSA-N |
SMILES | COC(=O)[C@H]1Cc2c([nH]c3ccccc23)[C@@H](N1C(=O)CCl)c4ccc(cc4)C(=O)OC |
MDL Number | MFCD30187526 |
Specification
MW | 440.9 |
MF | C23H21ClN2O5 |
Product Notes | RSL3 is a ferroptosis activator in a VDAC-independent manner exhibiting selectivity for tumor cells bearing oncogenic RAS RSL3 binds inactivates GPX4 and thus mediates GPX4-regulated ferroptosis |
Special Remarks | Store at -20¡C |
Manufacturer | Apollo Scientific |
Country of Origin | United Kingdom |