Product Identifiers
Catalog # | NX11878 |
CAS Number | 1032568-63-0 |
PubChem CID | 135565596 |
Chemical Name | Copanlisib |
IUPAC Name | 2-amino-N-[7-methoxy-8-(3-morpholin-4-ylpropoxy)-2,3-dihydro-1H-imidazo[1,2-c]quinazolin-5-ylidene]pyrimidine-5-carboxamide |
Synonym | BAYÊ80-6946 |
InChI | InChI=1S/C23H28N8O4/c1-33-19-17(35-10-2-6-30-8-11-34-12-9-30)4-3-16-18(19)28-23(31-7-5-25-20(16)31)29-21(32)15-13-26-22(24)27-14-15/h3-4,13-14,25H,2,5-12H2,1H3,(H2,24,26,27) |
InChIKey | MWYDSXOGIBMAET-UHFFFAOYSA-N |
SMILES | COc1c(OCCCN2CCOCC2)ccc3C4=NCCN4C(=Nc13)NC(=O)c5cnc(N)nc5 |
MDL Number | MFCD18633201 |
Specification
MW | 480.5 |
MF | C23H28N8O4 |
Product Notes | Copanlisib is a potent and highly selective reversible PI3K inhibitor for PI3K_/_ with IC50 of 0.469 nM/3.72 nM. |
Manufacturer | Apollo Scientific |
Country of Origin | United Kingdom |