CAS: 872365-14-5 | Fevipiprant, >99%, NX65340
SKU: NX65340-1MG
Product Identifiers
Catalog # | NX65340 |
CAS Number | 872365-14-5 |
PubChem CID | 23582412 |
Chemical Name | Fevipiprant |
IUPAC Name | 2-[2-methyl-1-[[4-methylsulfonyl-2-(trifluoromethyl)phenyl]methyl]pyrrolo[2,3-b]pyridin-3-yl]acetic acid |
Synonym | NVP-QAW039 |
InChI | InChI=1S/C19H17F3N2O4S/c1-11-15(9-17(25)26)14-4-3-7-23-18(14)24(11)10-12-5-6-13(29(2,27)28)8-16(12)19(20,21)22/h3-8H,9-10H2,1-2H3,(H,25,26) |
InChIKey | GFPPXZDRVCSVNR-UHFFFAOYSA-N |
SMILES | Cc1c(CC(=O)O)c2cccnc2n1Cc3ccc(cc3C(F)(F)F)S(=O)(=O)C |
MDL Number | MFCD22548206 |
Specification
MW | 426.4 |
MF | C19H17F3N2O4S |
Assay | >99% |
Product Notes | Fevipiprant is a selective, potent, reversible competitive CRTh2 antagonist with an in vitro dissociation constant KD value of 1.1nM at the CRTh2 receptor and an IC50 value of 0.44 nM for inhibition of PGD2-induced eosinophil shape change in human whole blood. |
Special Remarks | Keep Cold |
Cat Number | BISN0035 |
Manufacturer | Apollo Scientific |
Country of Origin | United Kingdom |