Name: CAS: 871700-17-3 | Trametinib, NX65289
Brand: Apollo Scientific
SKU: NX65289-10MG
Price: 240.0 USD
Availability: InStock

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Product Identifiers

Catalog #	NX65289
CAS Number	871700-17-3
PubChem CID	11707110
Chemical Name	Trametinib
IUPAC Name	N-[3-[3-cyclopropyl-5-(2-fluoro-4-iodoanilino)-6,8-dimethyl-2,4,7-trioxopyrido[4,3-d]pyrimidin-1-yl]phenyl]acetamide
Synonym	JTP-74057, GSK 1120212
InChI	InChI=1S/C26H23FIN5O4/c1-13-22-21(23(31(3)24(13)35)30-20-10-7-15(28)11-19(20)27)25(36)33(17-8-9-17)26(37)32(22)18-6-4-5-16(12-18)29-14(2)34/h4-7,10-12,17,30H,8-9H2,1-3H3,(H,29,34)
InChIKey	LIRYPHYGHXZJBZ-UHFFFAOYSA-N
SMILES	CN1C(=O)C(=C2N(C(=O)N(C3CC3)C(=O)C2=C1Nc4ccc(I)cc4F)c5cccc(NC(=O)C)c5)C
MDL Number	MFCD17215075

Specification

MW	615.4
MF	C26H23FIN5O4
Product Notes	Trametinib is a highly specific and potent MEK12 inhibitor with IC50 of 0.92 nM1.8 nM, no inhibition of the kinase activities of c-Raf, B-Raf, ERK12.
Cat Number	BISN0128
Manufacturer	Apollo Scientific
Country of Origin	United Kingdom

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