Name: CAS: 1032350-13-2 | MK-2206 dihydrochloride, NX11874
Brand: Apollo Scientific
SKU: NX11874-10MG
Price: 231.0 USD
Availability: InStock

CAS: 1032350-13-2 | MK-2206 dihydrochloride, NX11874

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Product Identifiers

Catalog #	NX11874
CAS Number	1032350-13-2
PubChem CID	46930998
Chemical Name	MK-2206 dihydrochloride
IUPAC Name	8-[4-(1-aminocyclobutyl)phenyl]-9-phenyl-2H-[1,2,4]triazolo[3,4-f][1,6]naphthyridin-3-one;dihydrochloride
InChI	InChI=1S/C25H21N5O.2ClH/c26-25(12-4-13-25)18-9-7-17(8-10-18)22-19(16-5-2-1-3-6-16)15-20-21(27-22)11-14-30-23(20)28-29-24(30)31;;/h1-3,5-11,14-15H,4,12-13,26H2,(H,29,31);2*1H
InChIKey	HWUHTJIKQZZBRA-UHFFFAOYSA-N
SMILES	Cl.Cl.NC1(CCC1)c2ccc(cc2)c3nc4C=CN5C(=O)NN=C5c4cc3c6ccccc6
MDL Number	MFCD14584463

Specification

MW	480.4
MF	C25H23Cl2N5O
Product Notes	MK-2206 2HCl is a highly selective inhibitor of Akt1/2/3 with IC50 of 8 nM/12 nM/65 nM, respectively, showing no inhibitory activities against 250 other protein kinases observed.
Manufacturer	Apollo Scientific
Country of Origin	United Kingdom

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