CAS: 935666-88-9 | AZD1480, >99%, NX69669
SKU: NX69669-50MG
Product Identifiers
Catalog # | NX69669 |
CAS Number | 935666-88-9 |
PubChem CID | 16659841 |
Chemical Name | AZD1480 |
IUPAC Name | 5-chloro-2-N-[(1S)-1-(5-fluoropyrimidin-2-yl)ethyl]-4-N-(5-methyl-1H-pyrazol-3-yl)pyrimidine-2,4-diamine |
InChI | InChI=1S/C14H14ClFN8/c1-7-3-11(24-23-7)21-13-10(15)6-19-14(22-13)20-8(2)12-17-4-9(16)5-18-12/h3-6,8H,1-2H3,(H3,19,20,21,22,23,24)/t8-/m0/s1 |
InChIKey | PDOQBOJDRPLBQU-QMMMGPOBSA-N |
SMILES | C[C@H](Nc1ncc(Cl)c(Nc2cc(C)[nH]n2)n1)c3ncc(F)cn3 |
MDL Number | MFCD16038904 |
Specification
MW | 348.76 |
MF | C14H14ClFN8 |
Assay | >99% |
Product Notes | AZD1480 is a selective ATP-competitive JAK1/2 inhibitor with IC50 value of 1.3 and <0.4_nM, respectively, as well as shows inhibitory effect on JAK3 and Tyk2. |
Special Remarks | Store at -20¡C |
Cat Number | BISN0012 |
Manufacturer | Apollo Scientific |
Country of Origin | United Kingdom |